Paradoxical reaction (PR) in HIV negative patients with tuberculosis: Case series

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Tuberculosis paradoxical reaction.

T is endemic in this part of the world. We frequently encounter patients with both pulmonary and extrapulmonary tuberculosis regardless of whether they are infected with human immunodeficiency virus (HIV) or not. It is not uncommon for physicians to see clinical or radiological, or both, worsening of the disease while their patient is on anti-tuberculous treatment, the so-called paradoxical rea...

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Severe Paradoxical Reaction Requiring Tracheostomy in a Human Immunodeficiency Virus (HIV)-negative Patient with Cervical Lymph Node Tuberculosis

During drug treatment of tuberculous lymphadenitis, paradoxical response (PR) may occasionally occur. Continued treatment or lymph node aspiration improves PR without severe sequelae. However, we report a case of severe PR in a patient with cervical lymph node tuberculosis causing airway obstruction due to retropharyngeal lymph node swelling during antituberculous treatment. Tracheostomy and dr...

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A Case of Paradoxical Reaction after Treatment of Eyelid Tuberculosis

Dear Editor, We hereby present a case of paradoxical reaction after treatment of eyelid tuberculosis (TB) with anti-TB medication. An 89-year-old man presented with painful eyelid swelling and erythema of his left eyelid, which initially developed one month earlier (Fig. 1A); he was otherwise in a healthy condition. No history of ocular trauma or operation was reported. At the time of his first...

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TUBERCULOSIS Paradoxical reactions during tuberculosis treatment in patients with and without HIV co-infection

Background: It has been suggested that deterioration of tuberculosis (TB) during appropriate treatment, termed a paradoxical reaction (PR), is more common and severe in HIV positive individuals on highly active antiretroviral therapy (HAART). Method: A study was undertaken to determine the frequency of PR and its associated features in a population of HIV+TB+ patients and a similar sized group ...

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Paradoxical response in patients with CNS tuberculosis.

AIM To report paradoxical response, i.e. recurrence of appearance of fresh symptoms, physical and radiological signs in a patient who had previously shown improvement with appropriate anti-tubercular medicines. MATERIAL AND METHODS Ten out of 58 patients of CNS tuberculosis, diagnosed on basis of clinical, laboratory and radiological data that initially showed clinical response to therapy onl...

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ژورنال

عنوان ژورنال: International Journal of Infectious Diseases

سال: 2016

ISSN: 1201-9712

DOI: 10.1016/j.ijid.2016.02.868